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IBD Bioresource Principle Investigator: |
The Inflammatory Bowel Disease BioResource: Progressing from Genetics to Function and Clinical Translation in Crohn's Disease & Ulcerative Colitis. The IBD BioResource is being set up by the UK IBD Genetics Consortium and the NIHR BioResource to collect DNA and serum samples from a cohort of 25,000 individuals with Crohn’s disease or ulcerative colitis. By gaining more information on the genes involved in Crohn’s disease and ulcerative colitis and by understanding the differences in their function and integrating information regarding environmental influences including the microbiota we hope to gain insights regarding causal mechanisms, potential new therapies and treatment approaches for IBD to reduce the burden of disease, and begin to think about a cure. |
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TIP Trial Principle Investigator: |
Targeting the intestinal immune system in digestive disease. Observational study sampling peripheral blood, intestinal tissue, mucous and faeces from healthy patients, or those with inflammatory bowel disease (IBD) or gastrointestinal cancers. Patients undergoing diagnostic endoscopy or gastrointestinal surgery with IBD or gastrointestinal cancers. |
