Research Studies - Neonatal Intensive Care Unit

MOM

Chief Investigator:
Dr Reynolds

Comparison of the mOm incubator with a standard incubator for the maintenance of thermal stability in preterm infants with user feedback

Feed1

Principle Investigator:
Dr Edwards

A randomised controlled trial of full milk feeds versus intravenous fluids with gradual feeding for preterm infants (30-33 weeks gestational age)

Dolphin

Principle Investigator:
Dr Edwards

In babies with HIE, does nutritional fortification with DHA, choline and UMP (intervention) plus usual care from birth to 12 months of age corrected for prematurity improve cognitive development (outcome) at 2 years of age corrected for prematurity, compared to babies receiving a matched control fortifier plus usual care (comparator)?

Multicentre blinded randomised placebo-controlled trial of 1,010 infants in 30 UK NHS tertiary neonatal units; 538 infants in the preterm group and 472 infants in the HIE group.

Harmonie

Principle Investigator:
Dr. Vennila Ponnusamy

A Phase IIIb randomized open-label study of nirsevimab (versus no intervention) in preventing hospitalizations due to respiratory syncytial virus in infants

Surepulse

Principle Investigator:
Dr Ponnusamy

To ascertain clinical advantage(s) of using SurePulse VS newborn heart rate monitor.

To ascertain the perceived reliability and heart rate acquisition time of SurePulse VS

To validate mapping the key roles and protocol changes for Delivery Room and Operating Theatre deployment of the SurePulse VS

iGBS3

Principle Investigator:
Dr Ponnusamy

Development of a serocorrelate of protection against invasive Group B Streptococcus disease (iGBS)

Neonin

Principle Investigator:
Dr Reynolds

Neonatal infection surveillance

Neoamro

Principle Investigator:
Dr Reynolds

Neonatal Antimicrobial Resistance and Outcome